| Antiepileptic, Antidiabetic, Antianginal, Antifungal |
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Lamotrigine
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INFORMATION FOR USE OF A MEDICAL PRACTITIONER, HOSPITAL OR LABORATORY |
| Each film coated tablet contains Lamotrigine……….100mg |
| PHARMACOLOGICAL CLASSIFICATION |
Antiepileptic/Anticonvulsant |
PHARMACOKINETICSLAMOTO is well absorbed from the gastrointestinal tract and peak plasma concentrations have been reported 2.5 hours after oral administration. It is widely distributed in the body and is reported to be about 55% bound to plasma protein. It is extensively metabolized in the liver and excreted almost entirely in the urine, principally as a glucuronide conjugate. It slightly induces its own metabolism and the half-life at steady state is reported to be about 24 hours. Lamotrigine is distributed into breast milk. |
LAMOTO is indicated for the treatment of · Epilepsy· Bipolar Disorder |
- Are you pregnant, trying to become pregnant or breast-feeding?
- Have you ever had a rash during previous treatment with lamotrigine or with any other antiepileptic drug?
- Are you taking any form of hormonal contraceptive (e.g. "the pill")
- Are you taking hormone replacement therapy (HRT)
- Do you have liver or kidney disease?
- Do you suffer from Parkinson’s disease?
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| You must take your medicine as the doctor tells you. It is important to take LAMOTO Tablets at the right time. Your doctor will decide which is the best dose for you, depending on your illness. Adults and children over 12 years old: The usual dose used to control epilepsy is between 100 mg and 400 mg, taken once daily or in two divided doses. When you first start taking LAMOTO, your doctor will prescribe a much lower dose than this and will then increase your dose gradually over a few weeks.Children between 2 and 12 years of age: The usual dose used to control epilepsy is between 1 mg and 15 mg per kilogram of your child’s body weight, taken once daily or in two divided doses. When your child first starts taking LAMOTO, your doctor will prescribe a much lower dose than this for your child and will then increase it gradually over a few weeks.Swallow Lamoto Tablets with a little water. |
| IF YOU MISS A DOSETake it as soon as you remember. If it is nearly time for the next dose, do not take the one you missed. Take the next dose at the usual time. Do not take a double dose to make up for the dose that you missed. If you miss more than one dose, or you are not sure what to do, ask your doctor or pharmacist. |
WHAT TO DO IF AN OVERDOSE IS TAKEN |
| If you accidentally take too many tablets, contact your doctor or nearest hospital accident department immediately |
Symptoms may include · coma; · involuntary eye movements; · loss of consciousness or coordination; · New or worsening seizures. |
| Please tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without prescription: |
· valproate · carbamazepine · phenytoin · phenobarbital · primidone, rifampicin · olanzapine or oxcarbazepine |
LAMOTO may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: · an unexpected skin reaction, e.g. a rash and/or a sore mouth or eyes · swelling around the face · if you get a high temperature, ‘flu-like’ symptoms, swollen glands or drowsiness, or if your epilepsy gets worse, particularly during the first month’s treatment with LAMOTO · if you start feeling very tired, if you get any unexpected bruising or bleeding, if you start getting more infections (e.g. colds) than usual, or if you develop a sore throat. Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately: |
- blurred vision, redness of the eye (conjunctivitis), dizziness, headache, difficulty sleeping, feeling or being sick, diarrhea, hallucinations, feeling irritable, aggressive, agitated or confused, pain (including back and joint pain)
- unsteadiness or loss of co-ordination when you walk
- if you have Parkinson’s disease, any worsening of your symptoms such as shaking of the arms or legs, rolling of the eyes or a chewing movement of the mouth
- unusual movements that you can’t control such as irregular jerking or shaking of the arms or legs
- If your seizures become more frequent.
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Disclaimer: Strictly meant for information purpose only. The above information should not be used at one’s own discretion nor should substitute your physician’s advice. |
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