| Antibiotic, Antibacterial, Penicellin, |
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Gatifloxacin
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| INFORMATION FOR USE OF A MEDICAL PRACTITIONER, HOSPITAL OR LABORATORY |
| Each film coated tablet contains: Gatifloxacin…..200 mg |
| Each film coated tablet contains: Gatifloxacin …..400 mg |
PHARMACOLOGICAL CLASSIFICATION |
GATI XL(Gatifloxacin) is a DNA gyrase inhibitor, and also inhibits topoisomerase IV. DNA gyrase (topoisomerase II) is an essential bacterial enzyme that maintains the superhelical structure of DNA. DNA gyrase is required for DNA replication and transcription, DNA repair, recombination, and transposition; inhibition is bactericidal. GATI XL (Gatifloxacin) is readily absorbed from the gastrointestinal tract following oral administration with an absolute bioavailability of 96%. Peak plasma concentrations are achieved within 1 to 2 hours of a dose. Gatifloxacin is widely distributed into body tissues and is approximately 20% bound to plasma proteins. It undergoes limited metabolism and has an elimination half-life of 7 to 14 hours. It is excreted primarily unchanged in the urine with less than 1% as metabolites. A small amount ( 5%) is also excreted unchanged in the faeces. GATI XL is indicated for the treatment of bacterial infections, such as certain types of lung, sinus, skin, and urinary tract bacterial infections. Gatifloxacin is also used to treat certain types of STDs or sexually transmitted diseases like gonorrhea Make sure you have told your doctor if you: |
- Are pregnant or think you may be pregnant, or are planning to become pregnant.
- Are breast feeding.
· Have ever had a severe allergic reaction to any medicine in the group of antibiotics · Have diabetes. · Have a rare condition known as congenital prolongation of the QTc interval. · kidney disease |
You must take your medicine as the doctor tells you. It is important to take GATI XL Tablets at the right time. Your doctor will decide which is the best dose for you, depending on your illness. The recommended dose is once a day for 1 to 14 days. Take the missed dose as soon as you remember it. If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to. Otherwise, take it as soon as you remember, and then go back to taking your doses as you would normally. If you are not sure whether to skip the dose, talk to your doctor or pharmacist. Do not take a double dose to make up for the dose that you missed. WHAT TO DO IF AN OVERDOSE IS TAKEN |
In that case do not delay, ask your doctor immediately what to do or contact your nearest hospital emergency department. Do this even if there are no signs of discomfort or poisoning. Symptoms of overdose may include: stomach pain, nausea, vomiting, and diarrhea Please tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without prescription, your doctor may wish to alter your dose of GATI XL if you are taking: · quinidine · procainamide · amiodarone · glipizide · digoxin · NSAIDs · Probenecid · live vaccines · warfarin |
Common side effects of GATI XL include: nausea, vomiting, stomach ache, diarrhea, dizziness, and headache. Serious side effects which may require medical attention include: · Numbness/tingling/weakness of arms/legs · Swelling of the ankles/hands/feet · Uncontrolled movements (e.g., tremors) · Vision changes |
· Keep all medicines out of the reach of children. · Store the tablets at room temperature and away from light and moisture |
| Disclaimer: Strictly meant for information purpose only. The above information should not be used at one’s own discretion nor should substitute your physician’s advice |
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